page
Home2
About2
Info2
Videos2
FAQ2
Contact3
Supplements2
Account2

 

Acid Repair (60 Tablets)

$37.66
Price: $37.66

Acid Repair

• Relieve Gastric Discomforts (e.g. upset stomach, belching, burping, bloat, episodes of
   indigestion, mild nausea)
• Support Healthy Balance of G.I. Flora
• Protect and Support the Integrity of the Gastric Mucosa
• Provide Antioxidant Protection for Gastric cells
• Inhibit Inflammatory Cytokine Expression in Gastric Cells

Acid Repair™ is a safe, high-potency, stable, patented zinc-carnosine complex with proven efficacy for the relief of gastric discomforts and protection of the gastric tissues. Acid Repair™ is effective as a stand alone or can be used to complement conventional gastric support and/or non-steroidal, anti-inflammatory protocols. The stomach-supportive benefits of zinc-carnosine have been demonstrated by more than 40 published studies.

 
All Arthritis Center of Riverside® Formulas Meet or Exceed cGMP Quality Standards 
 
Discussion:
     
     A wide range of treatments exist for the approximately 25 - 40% of Americans who suffer from symptoms related to dyspepsia. Commonly used antacids and anti-inflammatory drugs like NSAIDS used regularly impact digestion and the mucosal lining, resulting in a gastric environment friendly to a specific problematic bacterial strain.1 Whereas common stomach health products either neutralize or block gastric acid, Acid Repair™ supports the stomach's natural "cytoprotective" defense mechanisms. In human studies among 691 subjects, including clinical trials that showed improvement in endoscopic healing rates at both 4 and 8-week time points, zinc-carnosine exhibited high efficacy without any serious side effects.2
     Carnosine is a naturally-occurring di-peptide composed of the amino acids, L-histidine and fi-alanine. Carnosine can form stable complexes (ligands) with ion minerals like zinc and copper. Acid Repair™ contains a unique, patented zinc L-carnosine complex that has been in wide clinical use in Japan since 1994. Acid Repair™ differs chemically and biologically from a simple combination of zinc and L-carnosine and has been shown to be be approximately three times more effective than supplementing with either zinc sulfate or L-carnosine individually.3
     The healthy gastric mucosal lining protects the stomach unless it is overburdened by the damaging effects of stress, bacteri or irritating substances. Carnosine and zinc each have wound-healing properties; therefore it is not surprising that the zinc Lcarnosine ligand significantly protects and has been shown to heal the gastric lining, re-establishing balance within the stomach in a short time frame.4,5
     Zinc Lcarnosine complex does not rapidly breakdown in the stomach juice because it is a polymer. Japanese researchers found that this prolonged-release complex adheres to damaged areas of the stomach lining and forms a new mixed ligand complex with other body components (perhaps proteins, like albumin) at the site of the damage. At some point, a ligand exchange takes place freeing the Lcarnosine and zinc from the complex and making each available to support the healing process.6 Lcarnosine combats free radicals7 and zinc reduces inflammation.8 Animal studies have demonstrated the zinc-carnosine complex maintains the homeostasis of the gastric mucosa not only by promoting repair of damaged tissue,9 but also by its anti-oxidative, membrane-stabilizing capability10 and by protecting gastric cells via promotion of mucous production.11 The zinc-carnosine complex also blunts genetic pro-inflammatory signaling and of the release of pro-inflammatory cytokine expression in the gastric epithelial cells.12
     This complex has been shown to have selective anti-bacterial activity against a specific common strain known to weaken the gastric mucosa.6 The anti-urease activity of the complex may be responsible for its effect upon this bacteria.
 
Directions:
 
Swallow whole or chew one tablet with or after a meal, morning and evening; then 1-2 tablets daily for maintenance, or as directed by your healthcare professional.
 
Cautions:

Keep out of reach of children. Consult a healthcare practitioner before using.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 
 
References:
 
1. Sanduleanu S, et al. Double gastric infection with Helicobacter pylori and non-Helicobacter pylori bacteria du:
acid-suppressive therapy: increase of pro-inflammatory
cytokines and development of atrophic gastritis. Aliment Pharm
Ther. 2001 Aug;15(8):
1163-75 [PMID: 11472319]
2. Compilation of numerous studies presented in Jpn Pharmacol Ther 1992; (20)1
3. Korolkiewicz RP, et al. Polaprezinc exerts a salutary effect on impaired healing of gastric
lesions in diabetic rats. Dig Dis 2000;45(6):1200-1209
4. Nishiwaki H, Kato S, Sugamoto S, et al. Ulcerogenic and healing impairing actions of
monochloramine in rat stomachs: ef f of zinc L-carnosine, polaprezinc. J Physiol
Pharmacol 1999;50:183-95.
5. Arakawa T, Satoh H, Nakamura A, et al. Effects of zinc L-carnosine on gastric mucosal
and cell damage caused by ethan< rats. Correlation with endogenous prostaglandin E2.
Dig Dis Sci 1990;35:559-66.
6. Matsukura T, Tanaka H. Applicability of zinc complex of L-carnosine for medical use.
Biochemistry (Mosc). 2
Jul;65(7):817-23 [PMID: 10951100]
7. Carnosine and carnosine-related antioxidants: a review. Curr Med Chem. 2005;12
(20):2293-315 [PMID: 16181134]
8. Sempertegui F, Diaz M, et al. Low concentrations of zinc in gastric mucosa are
associated with increased severit Helicobacter pylori-induced inflammation. Helicobacter.
2007 Feb;12(l):43-8 [PMID: 17241300]
9. Seiki M. et al. [Effect of Z-103 on wound healing by dermal incision in guinea pigs] Nippon
Yakurigaku Zasshi. 1 Aug;100(2):165-72 [PMID: 1385281]
10. Arakawa, T., Satoh, H., Nakamura, A, Nakamura, H., Ishikawa, M., and Kobayashi, K
 (1988) Gastroenterology, 94, A12
11. Arakawa T, et al. Effects of zinc L-carnosine on gastric mucosal and cell damage caused
 by ethanol in rats. Correlation a endogenous prostaglandin E2. Dig Dis Sci. 1990 May;35
(5):559-66 [PMID: 2331952 ]
12. Tadahito Shimada, et al. Polaprezinc down-regulates pro-inflammatory cytokine-induced
 Nuclear Factor- B activation Interleukin-8 Expression in gastric epithelial cells . J
 Pharmacol Ther 1999; 291(1); 345-352
13. See ref #6
14. Kashimura H, et al. Polaprezinc, a mucosal protective agent, in combination with
 lansoprazole, Amoxycillin Clarithromycin increases the cure rate of Helicobacter pylori
 infection. Aliment Pharmacol Ther 1999;13:483-487

 

 

© 2014
Arthritis Center of Riverside
11725 Slate Avenue
Riverside, CA  92505
Tel: 951.352.1700
Fax: 951.352.9117

Website Tags  Website Index  Logout

 

     *The information in this website is not intended to replace a rheumatology textbook nor be a complete update of the rheumatology scientific literature.  It should not be misconstrued as personal medical advice.  Rather, it portrays Dr. Al Robert Franco's interests in the field of rheumatology, namely, the interrelationship between infections and rheumatic diseases and how this applies to the treatment of arthritis.